Which browser? 

And to be specific, do you explicitly want the browser to not cache anything, or would it suffice to clear the cache on exit? 

@piotrr We would like the set it so the browser didn't cache anything.  Eventually we would like to do this with Chrome, Safari and Firefox, but I'm starting with Chrome.  I did find scripts that I could run from Jamf that would clear the cache if that ends up being the best option.

@RachelGomez1619 Thank you for the info.  That allows someone at the Mac to manually disable the cache.  I'm hoping to find a way to remotely push that setting to a group of Macs through Jamf.  Any ideas?

Thank you,
Brent

@bstaple-98 Chrome and Edge can be managed using policies that can be set through configuration profiles. Create a configuration profile, add an Application & Custom Settings payload for External Applications, but then you'd need a JSON that defines what options are available, or type out the PLIST yourself. 

Google's resource for the manifest of settings is here: 

Set Chrome Browser policies on managed PCs - Chrome Enterprise and Education Help (google.com)

I know there are options to delete the cache upon closing the app, but there may be for disabling cache too.