You are already off to a good start.
You pointed out your first challenge. Your Genius Bar experience will not help much in a administrative capacity. Apple teaches you the consumer side of their products, MDM is a totally different beast. Troubleshooting MDM workflows is totally different than troubleshooting consumer workflows. Look over Apples Deployment and Management training even if you dont plan on taking the exam.
https://it-training.apple.com/tutorials/apt-deployment
Use Automated Device Enrollment for organization owned devices. This will require you to reprovision your existing iOS and macOS devices because thanks Apple. Do not rely on user enrollments.
I cannot stress this enough. Manage Macs like Macs, not like Windows. If you expect the same workflows and results out of MacOS as you do Windows you will have a lot of problems and disappointments. Apple builds a lot of their functions off of Automated Device Enrollment. Apple also does not give too poops about centralized identity management, do not domain bind. If you need some kind of central identity management look in to something like JAMF Connect for the most Windows like Experience, if password syncing is all you need look in to Apples SSO Connector, NoMad, Okta Verify, etc.
As an admin, accept anyone who does not work daily with Macs and iOS will complain as your data and workflow is not the “Windows way”. Be ready for a lot of pushback because you cannot replicate a given GPO configuration, or collect the same kind of data in the same way.
You mention Intune, just to note as Intune is also a MDM. You cannot use multiple MDM’s on one device, its JAMF or Intune. On macOS there is JAMF+Intune integration for conditional access, its not worth the effort. Microsoft has no idea how to support it, and JAMF can do conditional access by itself.