I work at a community college and have a lab with 22 iMacs in it. All were running 10.11.6 and I had just deployed several pieces of software to them including a policy that created an non-admin local user. I then ran a policy to reboot all of the machines and when I came into the lab all the machines are booted halfway and frozen. the reboot policy shows as pending on all machines. At some point there was a power failure and the JSS was down this morning but after hard rebooting ( attempting ) all the machines they still won't boot. I can get them to start up in safe mode and ran 'sudo jamf policy' from terminal but there response was no pending policy and the computers still won't boot.
Yeah, I also noticed in your post that you were experiencing this with Yosemite. I would think that it might be model specific but it really seems like with all 22 of them down that it's probably related to on of the software deployments. I'm going to start with Office 2016 and backtrack from there I guess.
We have a site license for Office. I would agree with you but we are new to Jamf and just starting to get the ball rolling. Those iMacs are the only computers that are currently enrolled and had office deployed to them. However that could be said for multiple Adobe CC products as well like, Acrobat, Photoshop, Dreamweaver, Indesign etc. so I've taken my test machine down to bare metal, re-installed the OS and re-enrolled it. I'll just go back on at a time and see if I can duplicate.