It allows an app to lock itself into single app mode and release itself from single app mode. Example would be a testing app. Once the user logs in it locks itself into the app so the user can't switch to safari. It can request to unlock itself once the user hits log out. In the spring Pearson recommended this as the way to do state testing for months. Then a couple weeks before testing said that it wasn't functioning with the update they just pushed.

Thanks Nick!

I just tested this with TestNav by adding it to a clone of my students configuration profile and I can report it worked pretty slick.

iPad works normally.
You can launch and exit the TestNav app anytime.
As soon as you sign in to take a test, it locks the iPad to TestNav.
Once you submit your results, it frees the iPad up again.

Does it work if the app store is removed? Last year it did not...

Is there any documentation for Autonomous Single App Mode using Jamf Pro? 

We are looking for the same info but don't see any documentation regarding.  Any help would be greatly appreciated.