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Buy Hydroxychloroquine 200/400 mg Online - Uses, Cost and Side Effects! Generic Plaquenil (hydroxychloroquine) is an oral medication used to treat malaria, lupus, rheumatoid arthritis and other inflammatory/autoimmune conditions. The typical dosing of Plaquenil for diseases like rheumatoid arthritis is 200-400 mg per day, with the dose depending on the patient's body weight. It works by modifying the immune system’s response and suppressing inflammation. Plaquenil comes in 200 mg tablets, often as a generic hydroxychloroquine. While effective, side effects like retinopathy, muscle weakness and heart problems can occur. Brand/generic names include Plaquenil, Hydroxychloroquine, Quensyl, Hydroquin, and HCQS. Recently Plaquenil received Emergency Use Authorization for COVID-19 though its efficacy remains debated. For certain patients, Plaquenil can provide substantial disease control, but ongoing eye exams are critical.