Since the release of the Safari 10 update, we've encountered a strange issue where a small handful of clients will no longer open the browser. Nothing in the logs and not even a single bounce in the dock when clicked. It occurs under all users on the affected machine and when opened via the Terminal, all that's returned is "LSOpenURLsWithRole() failed with error -10699 for the file /Applications/Safari.app"
What's even stranger is Safari can be opened by Show Package Contents on Safari.app then opening the executable within the Contents/MacOS folder.
Anyone have any ideas?
A reinstall ended up fixing it for my clients, if you need the download and don't want to hunt down a machine that hasn't received it yet, you can download it from Apple here: